Did you have any particular V air floor in mind re the comparison?
The Aerotec is the only V air floor that takes the V right from bow to transom. If you compare it to the usual air deck/floor model the only difference in regard to your questions is it leans more to one side when out of the water but there's little difference launching and beaching. Re fishing the floor inside slopes each side to the middle which isn't ideal for fishing.
All the other V air floor makes have an underneath V that flattens towards the transom in a similar way to a standard airdeck or alloy deck so they are totally the same to handle at beach/slipway. Internally they have slightly sloping floors but not as bad as the Aerotec.
One point that may or may not be an issue for you is the V air floor models (like the Honwave models) don't usually have any void between inner and outer floor so any water that splashes in is present around your feet/kit. The Aerotec has a small but sufficient void and flat airdeck or ally floor models have a void that will take quite a bit of splash before it comes above floor level.
OK my comments re the V air floor apply to that. No difference to any other SIB to launch or beach, slightly sloping inner floor and no void for splashed water.
Must mention they also need a very expensive (and often a bit wobbly) transom wheel type with a leg that curves around those rear floor tabs.
The comparison between an Inflatable V air mat and a plain flat one is that on the latter will be able to stand up, fish, carry different items such as fuel, water jerry cans much nicer than on the V air mat...