Jon
Tell us a bit more about what you are thinking of doing.
Is this to hang on to the trailer if the hitch fails? In which case I would use chain with a shackle, not a karabiner.
Is to activate the emergency brake if the hitch fails? In which case you'd probably be OK, but a simple spring clip is sufficient.
Is it to lower the trailer down a slip way? In which case there might possibly be an application for a karabiner.
Or D, none of the above
John